个人简介

姓       名：胡翠华  

出生年月：1980-4

学历学位：研究生/博士

职       称：讲师

所在系所：国家纳米操纵与制造国际联合研究中心

电子邮件：huch@cust.edu.cn

指导研究生所属学科及导师类别：电子科学与技术、硕士生导师

      研究领域：单癌细胞微纳测量与操纵、超分子药物传递体系的构建与表征；靶向抗癌肽的设计及机理研究；中药活性提取物抗癌活性及其对单癌细胞物理特性、生物学特性影响的研究。

      胡翠华，长春理工大学国家纳米操纵与制造国际联合研究中心教师，博士。主要在基于AFM检测技术在抗肿瘤、抗菌、抗病毒活性成分的筛选、活性及机理研究方面开展科研工作。作为项目负责人承担科技部项目子课题、教育厅项目。发表SCI论文14篇，EI论文1篇，第一作者以及共同一作7篇，通讯作者3篇，其中一区文章1篇，2区文章2篇。

教育经历

2015年9月至2018年4月，吉林大学生命科学学院生物化学与分子生物学，博士学位

2003年9月至2006年6月，吉林大学药学院药理学专业，硕士学位

1999年9月至2003年6月，华北理工大学药学系，学士学位

工作经历

2019年5月-至今，长春理工大学电信学院纳米中心，教师

2006年7月至2015年8月，长春金赛药业有限责任公司，国际注册部

代表性科研项目

单癌细胞操纵与测量(2017YFE0112100-03)子课题编号KYC-JC-XM-2018-155

代表性论文

(1) Hu Cuihua; Ma Ningning; Li Fei; Fang Yu; Liu Yao; Zhao Linlu; Qiao Shanpeng; Li Xiumei; Jiang Xiaojia; Li Tiezhu; Shen Fangzhong; Huang Yibing;* Luo Quan; Liu Junqiu*; Cucurbit[8]uril-Based Giant Supramolecular Vesicles: Highly Stable, Versatile Carriers for Photoresponsive and Targeted Drug Delivery, ACS Appl Mater Interfaces, 2018.2.7, 10 (5): 4603-4613.

(2) Hu Cuihua; Huang Yibing; Chen Yuxin*; Targeted Modification of the Cationic Anticancer Peptide HPRP-A1 with iRGD To Improve Specificity, Penetration, and Tumor-Tissue Accumulation, Molecular Pharmaceutics, 2019.2.4, 16(2): 561~572.

(3) Hu Cuihua; Chen Xiaolong; Huang Yibing; Chen Yuxin*; Co-administration of iRGD with peptide HPRP-A1 to improve anticancer activity and membrane penetrability. Scientific Reports, 2018.2.2, 8(1): 1~14.

(4) Hu Cuihua; Chen Xiaolong; Huang Yibing; Chen Yuxin *; Synergistic effect of the pro-apoptosis peptide kla-TAT and the cationic anticancer peptide HPRP-A1. Apoptosis, 2018.2, 23(2): 132~142.

(5) Hu Cuihua; Chen Xiaolong; Huang Yibing; Chen Yuxin *; Co-administration of kla-TAT peptide and iRGD to enhance the permeability on A549 3D multiple sphere cells and accumulation on xenograft mice. Chemical Biology & Drug Design, 2018.8 92(2): 1567~1575.

（6）Xiaolong Chen, Cuihua Hu, Yanan Zhang, Wenjing Hao, Xu He, Qing Li, Yuxi Huang, Yibing Huang, Yuxin Chen. Anticaner Activity and Mechanism of Action of kla-TAT peptide. International Journal of Peptide Research and Therapeutics.

(7) Wenjing Hao, Cuihua Hu, Yibing Huang, Yuxin Chen. Coadministration of kla peptide with HPRP-A1 to enhance anticancer activity. Plos One.

(8) Mingyan Gao, Jing Hu, Ying Wang, Mengnan Liu, Jianfei Wang, Zhengxun Song, Hongmei Xu, Cuihua Hu*, Zuobin Wang*. Controlled Self-Assembly of λ-DNA Networks with the Synergistic Effect of a DC Electric Field. The Journal of Physical Chemistry. 2019, 123, 9809-9818.

(9) Evaluations of 5-fluorourcil treated Lung cancer cells by Atomic Force Microscope. Xiaolin Jiang, Ke Ma*, Cuihua Hu*, Mingyan Gao, Jiashuo Zhang, Ying Wang, Yujuan Chen, Zhengxun Song, Zuobin Wang*. 2013,00,1-3.

(10) Chenchen Xie, Ran Ding, Xinyue Wang, Cuihua Hu, Jin Yan, Wenxiao Zhang, Ying Wang, Yingmin Qu, Shuye Zhang, Peng He, Zuobin Wang. A disulfiram-loaded electrospun poly (vinylidene fluoride) nanofibrous scaffold for cancer treatment. Nanotechnology 31(2020) 115101(8pp).

(11) Jing Hu, Jie Jiao, Ying Wang, Mingyan Gao, Zhengcheng Lu, Fan Yang, Cuihua Hu, Zhengxun Song, Yujuan Chen, Zuobin Wang. Effect of extract from ginseng rust rot on the inhibition of human hepatocellular carcinoma cells in vitro. Micron 124(2019)102710.

(12) Jie Zhu, Yibing Huang, Mingxia Chen, Cuihua Hu, Yuxin Chen. Functional Synergy of Antimicrobial peptides and Chlorhexidene Acetate Against Gram-Negative-Gram-positive Bacteria and a Fungus in Vitro and in Vivo. Infection and Drug Resistance. 2019:12 3227-3239.

(13) Jie Zhu, Yibing Huang, Cuihua Hu, Yuxi Huang, Mingxia Chen, Xu He, Yanan Zhang, Yiou Wang. Yuxin Chen. International Journal of Peptide Research and Therapeutics.

(14) Mingyan Gao, Yuxi Huang, Cuihua Hu*, Jing Hu, Ying Wang, Yujuan Chen, Yibing Huang, Guical Song, Zhengxun Song, Zuobin Wang*. Selective Anticancer Effect of Phellinus Linteus on Epidermoid Cell lines Studied by Atomic Force Microscopy. IEEE Nanotechnology Magazine. 2021. 12.

社会兼职

ACS Appl Mater Interfaces杂志审稿人