个人简介
姓 名：高明燕
职务：长春理工大学中山研究院 科研教师
邮箱：gmy@cust.edu.cn
研究领域：纳米操纵、微纳制造、纳米测量、生物纳米检测
高明燕，长春理工大学博士，英国Warwick大学联合培养博士
教育经历
2022年毕业于长春理工大学电子科学与技术专业，获工学博士学位；
2021年于英国Warwick大学工程学院接受博士联合培养；
2018年毕业于长春理工大学化学专业，获理学硕士学位；
2015年毕业于青岛大学化学专业，获理学学士学位。
资质与认定
2023年获吉林省高等教育教师资质
研究方向
纳米操纵、微纳制造、纳米测量、生物纳米检测
指导与教学
累计指导硕士研究生4名，博士研究生2名。
代表性科研项目
主持和参与纵向横向科研/教研项目10余项
科研项目
主持项目：
2023年 纳米操纵、制造与测量国际会议专业技术支持与服务项目
参与项目：
2022年 欧盟地平线计划H2022项目，Emerging Nanoscopy for Single Entity Characterisation（ENSIGN，No. 101086226）
2022年 欧盟地平线计划H2022项目，Laser Interference Lithography Based 4D-printing of Nanomaterials（L4DNANO，No. 101086227）
2023年 科技部国家重点研发计划项目（政府间国际科技创新合作重点专项），面向单个物体表征的纳米显微技术
2023年 科技部国家重点研发计划项目（政府间国际科技创新合作重点专项），面向生物和工程领域应用的激光干涉光刻微纳结构4D打印
2023年 面向生物和工程领域应用的激光干涉光刻微纳结构4D打印-任务一、非共面多光束激光干涉光场分布规律及三维空间光场调控机理
2023年 一种非激光的650 nm红光光源器件开发
2023年 海参活性物质协同PD-1抑制剂应用于肿瘤细胞检测方法开发
2023年 光电、纳米技术粤港澳大湾区国际学术研讨系列活动
2023年 表面纳米结构表征测试技术服务
2023年 用于寒地新型绿色建筑功能性微结构膜研究
2023年 微流控芯片制造技术服务
2023年 亚微米二维光栅器件加工技术服务
2023年 人体血清样本中miRNA124和miRNA210的荧光实时定量PCR检测
代表性论文
1. Mingyan Gao, Jing Hu, Wang Ying, Mengnan Liu, Jianfei Wang, Zhengxun Song, Hongmei Xu, Cuihua Hu* and Zuobin Wang*. Controlled Self-Assembly of lambda-DNA Networks with the Synergistic Effect of a DC Electric Field. Journal of Physical Chemistry B, 2019, 46(123): 9809-9818.
2. Mingyan Gao, Jing Hu, Jianfei Wang, Mengnan Liu, Xiaona Zhu, Sadaf Saeed, Cuihua Hu*, Zhengxun Song, Hongmei Xu and Zuobin Wang*. Self-Assembly of DNA Molecules in Magnetic Fields. Nanotechnology, 2021, 33(6): 065603.
3. Mingyan Gao, Jing, Hu, Bo Zhao* and Zhelin Liu*, Synthesis of Temperature Dependent Mn3O4 Nanowires for Asymmetric Supercapacitor Cell. Journal of Applied Electrochemistry, 2020, 50(7):767-777.
4. Mingyan Gao, Xiaofeng Wu, Haifang Qiu, Qingfan Zhang, Keke Huang, Shouhua Feng, Ying Yang, Tingting Wang, Bo Zhao *and Zhelin Liu. Reduced graphene oxide-mediated synthesis of Mn3O4 nanomaterials for an asymmetric supercapacitor cell. RSC Advances, 2018, 8, 20661.
5. Mingyan Gao, Jing Hu, Jianfei Wang, Mengnan Liu, Xiaona Zhu, Liguo Tian, Cuihua Hu, Zhengxun Song, Hongmei Xu and Zuobin Wang*. Study on the Conductivity of DNA Molecules under Magnetic Fields. Proc. IEEE 3M-NANO, 2021, 134-137.
6. Mingyan Gao, Yuxi Huang, Cuihua Hu*, Jing Hu, Ying Wang, Yujuan Chen, Yibing Huang, Guicai Song, Zhengxun Song and Zuobin Wang*. Selective Anticancer Effect of Phellinus Linteus on Epidermoid Cell Lines Studied by Atomic Force Microscopy: Anticancer Activity on A431 Cancer Cells and Low Toxicity on HaCat Normal Cells. IEEE Nanotechnology Magazine, 2021, 15(1): 4-16.
7. Ying Wang, Mingyan Gao, Yingmin Qu, Jing Hu, Ying Xie, Ziyu Liu, Zhengxun Song, Hongmei Xu, Zhankun Weng and Zuobin Wang*. Effects of AC/DC Electric Fields on Stretching DNA Molecules. Nano, 2020, 15(05): 2050065. .
8. Jing Hu, Mingyan Gao, Zuobin Wang*, Yujuan Chen*. Review on the Applications of Atomic Force Microscopy Imaging in Proteins. Micron, 2022, 159: 103293.
9. Jing Hu, Mingyan Gao, Zuobin Wang*, Yujuan Chen*, Zhengxun Song, Hongmei Xu. Direct Imaging of Antigen-antibody Binding by Atomic Force Microscopy. 2021, 11(1): 293-300.
10. Jing Hu, Mingyan Gao, Ying Wang, Mengnan Liu, Jianfei Wang, Jiani Li, Zhengxun Song, Yujuan Chen*, Zuobin Wang*. Imaging the Substructures of Individual IgE Antibodies with Atomic Force Microscopy. Langmuir, 2019, 35(46): 14896-14901.
11. Junxi Wang, Mingyan Gao, Lixin Yang, Yuxi Huang, Jiahe Wang, Bowei Wang, Guicai Song, Zuobin Wang. Cell recognition based on atomic force microscopy and modified residual neural network. Journal of Structural Biology, 2023, 215(3): 107991.
12. Ying Wang, Ying Xie, Mingyan Gao, Wenxiao Zhang, Lanjiao Liu, Yingmin Qu, Jiajia Wang, Cuihua Hu, Zhengxun Song and Zuobin Wang*. Electrical conductivity measurement of λ DNA molecules by conductive atomic force microscopy. Nanotechnology, 2021, 33(5): 055301.
13. Jing Hu, Jie Jiao, Ying Wang, Mingyan Gao, Zhengcheng Lu, Fan Yang, Cuihua Hu, Zhengxun Song, Yunjuan Chen and Zuobin Wang*. Effect of Extract from Ginseng Rust Rot on the Inhibition of Human Hepatocellular Carcinoma Cells in Vitro. Micron, 2019, 124: 102710.
14. Xiaolin Jiang, Ke Ma, Cuihua Hu, Mingyan Gao, Jiashuo Zhang, Ying Wang, Yujuan Chen, Zhengxun Song and Zuobin Wang*. Evaluations of 5-fluorourcil Treated Lung Cancer Cells by Atomic Force Microscope. Analytical Methods, 2019, 11: 4977-4982.
15. Jing Hu, Yujuan Chen*, Jiajing Zhu, Mingyan Gao, Jiani Li, Zhengxun Song, Hongmei Xu, Zuobin Wang*. Anti-degranulation Response of Herbal Formula in RBL-2H3 Cells. Micron, 2020, 130: 102819.
16. Jiayao Yuan, Zuobin Wang*, Jianjun Dong, Mingyan Gao, Fan Yang, Hao Sun. Effect of resveratrol on SH-SY5Y cells studied by atomic force microscopy. Micron, 2024, 177: 103577.
17. Xiaona Zhu, Zegao Wang, Jing Hu, Zhengcheng Lu, Mingyan Gao, Ying Wang, Zhengxun Song, Mingdong Dong*, Zuobin Wang, Lasse Hyldgaard Klausen. Ion-modulated photoluminescence of MoS2 nanoflakes for cell viability detection. New Journal of Chemistry, 2022, 46: 22441.
18. Ying Wang, Ke Ma, Jiajia Wang, Yihui Wang, Li Li, Ziyu Liu, Jing Hu, Mingyan Gao and Zuobin Wang*. Effects of alternating electric field on the imaging of DNA double helix structure by atomic force microscope.Applied Nanoscience, 2020, 10: 3517-3524.
19. Huijuan Shen, Yaode Wang, Liang Cao, Ying Xie, Ying Wang, Qinhan Zhang, Wenxiao Zhang, Shenzhi Wang, Zhuang Han, Xiaona Zhu, Miaomiao Yu, Ri Liu, Mingyan Gao, Changli Li, Zhankun Weng*, Zuobin Wang*. Fabrication of Periodical Micro-stripe Structure of Polyimide by Laser Interference Induced Forward Transfer Technique. 2021, 541: 148466.
发明专利
授权国家发明专利2项
1. 王作斌，胡婧，陈玉娟，焦洁，王莹，高明燕，卢征程，杨帆，胡翠华，宋正勋，锈腐病人参提取物在制备用于治疗肿瘤的药物中的应用，ZL 201910498898.2，申请日期：2019.6.11，授权日期：2021.8.6
2. 王作斌，胡婧，陈玉娟，高明燕，姜晓琳，董莉彤，宋正勋，许红梅，翁占坤，一种利用原子力显微术对生物素化抗体-IgE免疫复合物直接成像的方法，ZL 202010719926.1，申请日期：2020.7.24，授权日期：2023.01.03
获奖
2021年 第七届中国国际“互联网+”大学生创新创业大赛铜奖，吉林省金奖
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Curriculum Vitae
Gao Mingyan, Ph.D., Teacher of Zhongshan institute of Changchun University of Science and Technology. She received her PhD of Engineering from Changchun University of Science and Technology. She received a one-year PhD co-training at the School of Engineering, University of Warwick, UK. She has led and participated in more than 10 projects. She has published 6 papers as the first author and more than 10 papers as a co-author. She has obtained 2 invention patents.
E-mail: gmy@cust.edu.cn
Education and Training:
2022, Received the degree of Doctor of Engineering, CUST, China.
2021, Doctoral co-training at the School of Engineering, University of Warwick, UK.
2018, Received Master's degree of Science, CUST, China.
2015, Received Bachelor's degree of Science, Qingdao University, China.
Other qualification:
2023, qualified as a teacher of higher education in Jilin Province.
Academic Title and Position:
2023/02-present, Scientific Research teacher, Zhongshan Institute of Changchun University of Science and Technology, China.
Research Interests:
Nano manipulation, Micro and nano manufacturing, Nano measurement, Biological and nano detection
Teaching Modules:
Supervised and supervising: 4 Master students, 2 PhD students.
Research projects:
Hosted and participated in more than 10 projects.
Projects hosted：
2023年 纳米操纵、制造与测量国际会议专业技术支持与服务项目
Projects participated:
2022年 欧盟地平线计划H2022项目，Emerging Nanoscopy for Single Entity Characterisation（ENSIGN，No. 101086226）
2022年 欧盟地平线计划H2022项目，Laser Interference Lithography Based 4D-printing of Nanomaterials（L4DNANO，No. 101086227）
2023年 科技部国家重点研发计划项目（政府间国际科技创新合作重点专项），面向单个物体表征的纳米显微技术
2023年 科技部国家重点研发计划项目（政府间国际科技创新合作重点专项），面向生物和工程领域应用的激光干涉光刻微纳结构4D打印
2023年 面向生物和工程领域应用的激光干涉光刻微纳结构4D打印-任务一、非共面多光束激光干涉光场分布规律及三维空间光场调控机理
2023年 一种非激光的650 nm红光光源器件开发
2023年 海参活性物质协同PD-1抑制剂应用于肿瘤细胞检测方法开发
2023年 光电、纳米技术粤港澳大湾区国际学术研讨系列活动
2023年 表面纳米结构表征测试技术服务
2023年 用于寒地新型绿色建筑功能性微结构膜研究
2023年 微流控芯片制造技术服务
2023年 亚微米二维光栅器件加工技术服务
2023年 人体血清样本中miRNA124和miRNA210的荧光实时定量PCR检测
Papers:
1. Mingyan Gao, Jing Hu, Wang Ying, Mengnan Liu, Jianfei Wang, Zhengxun Song, Hongmei Xu, Cuihua Hu* and Zuobin Wang*. Controlled Self-Assembly of lambda-DNA Networks with the Synergistic Effect of a DC Electric Field. Journal of Physical Chemistry B, 2019, 46(123): 9809-9818.
2. Mingyan Gao, Jing Hu, Jianfei Wang, Mengnan Liu, Xiaona Zhu, Sadaf Saeed, Cuihua Hu*, Zhengxun Song, Hongmei Xu and Zuobin Wang*. Self-Assembly of DNA Molecules in Magnetic Fields. Nanotechnology, 2021, 33(6): 065603.
3. Mingyan Gao, Jing, Hu, Bo Zhao* and Zhelin Liu*, Synthesis of Temperature Dependent Mn3O4 Nanowires for Asymmetric Supercapacitor Cell. Journal of Applied Electrochemistry, 2020, 50(7):767-777.
4. Mingyan Gao, Xiaofeng Wu, Haifang Qiu, Qingfan Zhang, Keke Huang, Shouhua Feng, Ying Yang, Tingting Wang, Bo Zhao *and Zhelin Liu. Reduced graphene oxide-mediated synthesis of Mn3O4 nanomaterials for an asymmetric supercapacitor cell. RSC Advances, 2018, 8, 20661.
5. Mingyan Gao, Jing Hu, Jianfei Wang, Mengnan Liu, Xiaona Zhu, Liguo Tian, Cuihua Hu, Zhengxun Song, Hongmei Xu and Zuobin Wang*. Study on the Conductivity of DNA Molecules under Magnetic Fields. Proc. IEEE 3M-NANO, 2021, 134-137.
6. Mingyan Gao, Yuxi Huang, Cuihua Hu*, Jing Hu, Ying Wang, Yujuan Chen, Yibing Huang, Guicai Song, Zhengxun Song and Zuobin Wang*. Selective Anticancer Effect of Phellinus Linteus on Epidermoid Cell Lines Studied by Atomic Force Microscopy: Anticancer Activity on A431 Cancer Cells and Low Toxicity on HaCat Normal Cells. IEEE Nanotechnology Magazine, 2021, 15(1): 4-16.
7. Ying Wang, Mingyan Gao, Yingmin Qu, Jing Hu, Ying Xie, Ziyu Liu, Zhengxun Song, Hongmei Xu, Zhankun Weng and Zuobin Wang*. Effects of AC/DC Electric Fields on Stretching DNA Molecules. Nano, 2020, 15(05): 2050065. .
8. Jing Hu, Mingyan Gao, Zuobin Wang*, Yujuan Chen*. Review on the Applications of Atomic Force Microscopy Imaging in Proteins. Micron, 2022, 159: 103293.
9. Jing Hu, Mingyan Gao, Zuobin Wang*, Yujuan Chen*, Zhengxun Song, Hongmei Xu. Direct Imaging of Antigen-antibody Binding by Atomic Force Microscopy. 2021, 11(1): 293-300.
10. Jing Hu, Mingyan Gao, Ying Wang, Mengnan Liu, Jianfei Wang, Jiani Li, Zhengxun Song, Yujuan Chen*, Zuobin Wang*. Imaging the Substructures of Individual IgE Antibodies with Atomic Force Microscopy. Langmuir, 2019, 35(46): 14896-14901.
11. Junxi Wang, Mingyan Gao, Lixin Yang, Yuxi Huang, Jiahe Wang, Bowei Wang, Guicai Song, Zuobin Wang. Cell recognition based on atomic force microscopy and modified residual neural network. Journal of Structural Biology, 2023, 215(3): 107991.
12. Ying Wang, Ying Xie, Mingyan Gao, Wenxiao Zhang, Lanjiao Liu, Yingmin Qu, Jiajia Wang, Cuihua Hu, Zhengxun Song and Zuobin Wang*. Electrical conductivity measurement of λ DNA molecules by conductive atomic force microscopy. Nanotechnology, 2021, 33(5): 055301.
13. Jing Hu, Jie Jiao, Ying Wang, Mingyan Gao, Zhengcheng Lu, Fan Yang, Cuihua Hu, Zhengxun Song, Yunjuan Chen and Zuobin Wang*. Effect of Extract from Ginseng Rust Rot on the Inhibition of Human Hepatocellular Carcinoma Cells in Vitro. Micron, 2019, 124: 102710.
14. Xiaolin Jiang, Ke Ma, Cuihua Hu, Mingyan Gao, Jiashuo Zhang, Ying Wang, Yujuan Chen, Zhengxun Song and Zuobin Wang*. Evaluations of 5-fluorourcil Treated Lung Cancer Cells by Atomic Force Microscope. Analytical Methods, 2019, 11: 4977-4982.
15. Jing Hu, Yujuan Chen*, Jiajing Zhu, Mingyan Gao, Jiani Li, Zhengxun Song, Hongmei Xu, Zuobin Wang*. Anti-degranulation Response of Herbal Formula in RBL-2H3 Cells. Micron, 2020, 130: 102819.
16. Jiayao Yuan, Zuobin Wang*, Jianjun Dong, Mingyan Gao, Fan Yang, Hao Sun. Effect of resveratrol on SH-SY5Y cells studied by atomic force microscopy. Micron, 2024, 177: 103577.
17. Xiaona Zhu, Zegao Wang, Jing Hu, Zhengcheng Lu, Mingyan Gao, Ying Wang, Zhengxun Song, Mingdong Dong*, Zuobin Wang, Lasse Hyldgaard Klausen. Ion-modulated photoluminescence of MoS2 nanoflakes for cell viability detection. New Journal of Chemistry, 2022, 46: 22441.
18. Ying Wang, Ke Ma, Jiajia Wang, Yihui Wang, Li Li, Ziyu Liu, Jing Hu, Mingyan Gao and Zuobin Wang*. Effects of alternating electric field on the imaging of DNA double helix structure by atomic force microscope.Applied Nanoscience, 2020, 10: 3517-3524.
19. Huijuan Shen, Yaode Wang, Liang Cao, Ying Xie, Ying Wang, Qinhan Zhang, Wenxiao Zhang, Shenzhi Wang, Zhuang Han, Xiaona Zhu, Miaomiao Yu, Ri Liu, Mingyan Gao, Changli Li, Zhankun Weng*, Zuobin Wang*. Fabrication of Periodical Micro-stripe Structure of Polyimide by Laser Interference Induced Forward Transfer Technique. 2021, 541: 148466.
Patents:
1. 王作斌，胡婧，陈玉娟，焦洁，王莹，高明燕，卢征程，杨帆，胡翠华，宋正勋，锈腐病人参提取物在制备用于治疗肿瘤的药物中的应用，ZL 201910498898.2，申请日期：2019.6.11，授权日期：2021.8.6
2. 王作斌，胡婧，陈玉娟，高明燕，姜晓琳，董莉彤，宋正勋，许红梅，翁占坤，一种利用原子力显微术对生物素化抗体-IgE免疫复合物直接成像的方法，ZL 202010719926.1，申请日期：2020.7.24，授权日期：2023.01.03
Awards:
2021 Bronze Medal of the 7th China International "Internet +" College Students Innovation and Entrepreneurship Competition.